Summary: The notion of maximal non-pseudovaluation subring of an integral domain is introduced and studied. Let $R\subset S$ be an extension of domains. Then $R$ is called a maximal non-pseudovaluation subring of $S$ if $R$ is not a pseudovaluation subring of $S$, and for any ring $T$ such that $R \subset T\subset S$, $T$ is a pseudovaluation subring of $S$. We show that if $S$ is not local, then there no such $T$ exists between $R$ and $S$. We also characterize maximal non-pseudovaluation subrings of a local integral domain.